Disgraced Hollywood mogul Harvey Weinstein has lost his career, reputation and now his wife Georgina Chapman, as more women including Gwyneth Paltrow and Angelina Jolie continue to speak up to accuse him of decades of sexual harassment and assault.

After staying silent for several days Ms Chapman, 41, released a statement announcing she is leaving Weinstein as he faces an increasing string of allegations sparked by a New York Times report.

“My heart breaks for all the women who have suffered tremendous pain because of these unforgivable actions,” Ms Chapman told People. 

“I have chosen to leave my husband.”

She added, “Caring for my young children is my first priority and I ask the media for privacy at this time.”

Weinstein, 65, reportedly plans to enter a treatment facility but a source said he has not yet left the Los Angeles hotel where he and Chapman had been staying.

Weinstein, who has denied allegations of nonconsensual sex, initially said Chapman, who owns couture house Marchesa with her friend Keren Craig, “stands 100 per cent behind me.”

He told the New York Post, “Georgina and I have talked about this at length,” adding she is helping him become “a better human”.

Chapman, he said, will be “kicking my a––– to be a better human being and to apologise to people for my bad behaviour, to say I’m sorry, and to absolutely mean it.”

Now instead of just kicking his behind, she’s kicked him to the kerb, even as Weinstein plans to sue the Times over the article, accusing it of “reckless reporting” over its claims he’d reached settlements with eight women who had accused him of sexual harassment.

Amid the public relations storm the British designer, who wed Weinstein in December 2007, is not just making decisions about her private life, but is reportedly concerned about the future of Marchesa.

A red carpet mainstay, Marchesa’s success is heavily reliant on Chapman and Weinstein’s A-list friends like Anna Wintour, Heidi Klum and Blake Lively, who wear its creations for everything from the Oscars to their wedding day.

“No star is ever going to want to wear the brand again,” an anonymous New York fashion publicist told The Hollywood Reporter.

As per her statement, Chapman will also no doubt be concerned about the impact of the media scrutiny on her and Weinstein’s children, daughter India, seven, and son Dashiell, four.

Based between New York and London, the family appear tight-knit on social media, regularly holidaying together in exotic locales.

Chapman is always by Weinstein’s side at high-profile events like the Golden Globes and he, in turn, is a front-row regular at her shows.

https://www.instagram.com/p/BVgUZq-gKGO/?hl=en&taken-by=georginachapmanmarchesa

On the Friday after the news broke, Chapman was photographed stepping out of the family’s New York townhouse looking immaculate, even managing a smile.

A source told People while Chapman was “furious and embarrassed” by the allegations, she was more worried about the future of her business, which she co-founded with Craig in 2004.

The high-end company employs Chapman’s brother and several of her friends and is sold globally, producing elaborate evening and wedding gowns, handbags and jewellery.

Chapman has spent many years fighting suggestions Marchesa’s success is thanks to Weinstein’s influence and A-lister friends.

In an interview with Vogue, Weinstein insisted his wife had become a power player in her own right.

“Within a year or two, it became actresses calling me on the phone asking if she was available for them,” he said.

Whether the brand has forged its own path far enough to stand alone from Weinstein’s personal brand remains to be seen.

Of course, many have pointed out Chapman cannot be held accountable for her husband’s actions, and should not be punished as a result of them.

Weinstein himself told Vogue of his wife in 2013: “Unlike her husband, she’s really nice. People will believe that, trust me.”